The SCIENCE & RESEARCH
Of Biological Calcium in Humans
NOTE: Despite all of these massive scientific claims regarding the health benefits of calcium to cancer, blood pressure, kidney stones, bone fractures and menstrual disorders... the promoters of calcium products making reference to these facts in print and other media had been temporarily outlawed by the FTC which refuses to accept any of the massive scientific substantiation.
However, the scientific community offers far too much evidence and clinical studies to be denied such repression. What are they afraid of? Why does the FTC and other governmental agencies not want the general public to know about this important health related discoveries?
Scientific Publication Quotations on Calcium and Cancer Health Claims
“Coral Calcium Exhibited an inhibitory effect on the growth of cancer cells”
Yuji Hirota, Ph.D., Takashi Sugisaki, Ph.D., Medical Preventive Group Laboratory, MPG Co., Ltd. 2-41-18 Sumida, Sumida-ku, Tokyo, Japan 131
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“A protective effect of calcium on colorectal cancer, one of the most common malignancies in Western societies, has been supported by results of in vitro animal studies.”
Maria Elena Martenez and Walter C. Willett, Arizona Cancer Center, University of Arizona Health Sciences Center, Tucson, Arizona. And the Channing Laboratory, Harvard Medical School, Department of Nutrition, Boston Massachusetts, 10/30/97.
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“Adding dietary calcium markedly suppressed the diet induced hyper proliferation of epithelial calls (cancer).”
Lexun Xue, Martin Lipkin, Harrold Newark, Jiarmin Wang, Influence of Dietary Calcium on Diet Induced Epithelial Cell Hyperproliferation in Mice, Memorial Sloan-Kettering Cancer Center, Strang Cancer Prevention Center, New York, Cell Biology Laboratory Henan Medical University, China.
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“Higher calcium intake is associated with a reduced risk of distal colon cancer”
Kana Wu, Walter C. Willer, Charles S. Fuchs, Graham A. Colditz and Edward L. Giovannucci, “Calcium Intake and Risk of Colon Cancer in Women and Men”, Department of Nutrition, Harvard School of Public Health, Boston MA, Department of Nutrition and Epidemiology, Harvard School of Public Health, Channing Laboratory, Harvard Medical School.
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“The results of the present study show that there is a significant protective effect of calcium intake from drinking water against colon cancer”
Chun Yuh Yang, HuiFen Chiu, Shang Shyue Tsai and Ming Fen Cheng, “Calcium in Drinking Water and Risk of Death from Colon Cancer”, School of Public Health, Department of Pharmacology, Kao, Hsiung Medical College Taiwan.
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“The results of the study show that there may be a significant protective effect of calcium intake from drinking water on the risk of rectal cancer.”
Chug Yuh Yang and Hui Fen Chui, “Calcium in Drinking Water and Risk of Death from Rectal Cancer”, School of Public Health, Department of Pharmacology, Hsiung Medical College, Taiwan.
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“Higher levels of calcium intake were associated with reduced colon and rectal cancer risk”.
Pamela M. Marcus and Polly Newcomb, University of Wisconsin Comprehensive Cancer Center, Madison WI, International Journal of Epidemiology, 1998; 27;788-793.
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“These data support the hypothesis that higher calcium intake may decrease risk for colorectal neoplasms (cancer)”.
Sonia M. Boyapati, Robert M. Bostick, Katherine McGlynn, Michael Fina,./Walter Roufail, Kim Geisinger Michael Wargovich, Ann Coker, and James Hebert. Center for Health Services Research, Vanderbelt University, Nashville, TN, , Department of Epidemiology, Norman J Arnold School of Health, University of South Carolina., Wake Forrest University, University of Texas.
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“Both men and women who died of colorectal cancer had a lower mean calcium intake compared to the rest of the population”
Ingrid Slob, Johannes Lambregts, Alberine Schuit and Frans Kok, “Calcium Intake and Cancer Mortality in Dutch Civil Servants, Department of Epidemiology and Public Health, Agricultural University, The Netherlands
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“Supplemental calcium has been shown to reduce the recurrence of colonic adenomatous polyps in patients at increased risk for colonic neoplasm (cancer).”
Peter Holt, Carla Wolper, Steven Moss, Kan Yang and Martin Lipkin, Comparison of Calcium Supplementation on Epithelial Cell Proliferation and Differentiation”, Nutrition and Cancer, 41(1&2), 150-155, Department of Medicine , St Luke’s Roosevelt Hospital, Strang Cancer Prevention Center
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“Dietary calcium may inhibit colonic carcinogenisis promoted by high fat and low fiber diets.”
P. Rozen, Z Fireman, N. Fine, Y. Wax and E. Ron, “Oral Calcium Suppresses Increased Rectal Epithelial Proliferation of Persons at Risk of Colorectal Cancer”, Department of Gastroenterology, Tel-Aviv Medical Center, University of Israel, National Cancer Institute Bethesda, MD
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“Our data suggests that high calcium intake may lowers colorectal cancer risk”
Paul Terry, John Baron, Lief Bergkvist, Lars Holmberg, and Alicja Wolk, “Dietary Calcium and Risk of Colorectal Cancer: A prospective Study in Women”, Nutrition and Cancer, 43(1), 39-46, Department of Medical Epidemiology, Karolinska Institute, Stockholm, Sweden.
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“Calcium was found to significantly reduce tumor multiplicity”
G, Ranhotra, J Gelroth, B Glaser, P Schoening, and S Brown, “Cellulose and Calcium lower the Incidence of Chemically-Induced Colon Tumors in Rats”, Plant Foods for Human Nutrtion 54: 295-303, 1999, Kansas State University.
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“The article by Lipkin in the November 28 issue of the New England Journal of Medicine strongly suggests that calcium intake may play a part in the incidence of colorectal cancer”.
Genaro Palmieri, M.D., New England Journal of Medicine, University of Tennessee Medical Center
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“The ability of oral calcium supplementation to suppress rectal epithelial proliferation supports its potential to prevent development of colorectal carcinoma in high risk individuals”.
M. Thomas, J Thomson, and R Williamson, “Oral Calcium Inhibits Rectal Epithelial Proliferation in Familial Adenomatous Polyposis” Br. J. Surg, 1993, Vol. 80, April, 499-501, Department of Surgery, Royal Medical School, St Marks Hospital, London, England.
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“The chemo-preventive activity of calcium was suggested by epidemiological studies associating high dietary calcium with decreased colon cancer risk or mortality”.
Chemoprevention Branch and Agent Development Committee, Clinical Development Plan, Calcium
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“Habitual dietary calcium may contribute to nutritional modulation of colon cancer risk”
Mirjam Govers, Denise Termont, John Lapre, Jan Kleibeuker, Roel Vonk and Roelof Van Der Meer, “Calcium in Milk Precipitates Intestinal Fatty Acids and bbb Thus Inhibits Colonic Cytotoxicity in Humans”, Cancer Research, 3270-3275, July 15, 1996, Department of Nutrition, , University Hospital Groningen, The Netherlands
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“These inhibitory effects on metabolic factors suggest a preventive effect of dietary calcium on colon carcinogenisis”.
R. Van Der Meer, J Lapre, M. Govers, J Kleibeuker, “Mechanisms of the Intestinal Effects of milk products on Colon Cancer”, Cancer letters 114 (9197) 75-83, Department of Nutrition University Hospital, Groningen, The Netherlands
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.“In human subjects at increased risk for colon cancer, hyper-proliferation of colon epithelial cells was reduced after oral dietary supplementation with calcium”.
Harold Newark, and Martin Lipkin, Cancer Research (suppl) 52, 2067-2070, April1, 1992, Sloan Kettering Cancer Center, New York, Rutgers University College of Pharmacy, New Jersey.
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“Recent findings have indicated that dietary calcium can modulate and inhibit colon carginogenisis”.
Sergio Lamprecht and Martin Lipkin, “Chemoprevention of colon cancer by Calcium”, Strang Cancer Prevention Center, New York
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“Mediating effects of extra cellular calcium on cellular proliferation could provide a rationale for the use of calcium supplements for intervention in early phases of colon cancer.”
Eniko Kallay, M Bajina, Friedrick Wirba M.D., Stephan Kriwanek M.D., Meinrad Peterlik, PhD, M.D., Heide Cross PhD., “Dietary calcium and Growth modulation pf Human Cancer Cells”, Department of Experimental pathology, Department of Clinical pathology, University of Vienna Medical School, Vienna, Austria.
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“Recently we have shown that supplemental dietary calcium inhibits colonic epithelial proliferation which may decrease the risk of colon cancer”.
Mirjam Govers, Denise Termont, and Roelof Van Der Meer, “Mechanism of the Antiproliferative Effect of Calcium Supplements on Colonic Cancer.”, Department of Nutrition, Institute for Dairy Research, The Netherlands
Scientific Publication Quotations on Calcium and High Blood Pressure Health Claims
“These data suggest that supplementation of dietary calcium may contribute to a reduction of blood pressure in elderly patients with hypertension”.
Yasuyuki Takagi, Masaaki Fukase, Scoichiro Takata, Tadao Fujimi, and Takuo Fujitta, “Calcium Treatment of Essential Hypertension in Elderly Patients.”, Department of Medicine, Kobe University Scholl of Medicine, Kobe, Japan
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“Treatment with oral calcium represents well tolerated nonpharmacologic intervention that lowers blood pressure in patients with mild to moderate hypertension”.
David McCarron, M.D., Cynthia Morris PhD., “Blood Pressure Response to Oral Calcium in Persons with Mild to moderate Hypertension”, Annals of Internal Medicine, December 1985, Volume 103, Number 6, Published by the American College of Physicians, Portland Oregon.
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“If calcium intake of the general population were to increase to above 1200 mg, the incidence of hypertension in the elderly might be decreased”.
Ihab Hajjar, M.D., Clarence Grim, M.D., Theadore Kotchen, M.D., “Dietary Calcium Lowers the Age-Related Rise in Blood Pressure in the United States”, The NHANES Survey, Division of Geriatrics, Department of Internal Medicine, Palmetto Health Alliance University of South Carolina and the Department of Medicine, Medical College of Wisconsin, Milwaukee, WI.
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“Conclusion, Dietary calcium is inversely related to systolic blood pressure in young children”
Matthew Gillman, M.D., Susan Oliveria, MPH, Curtis Ellison, M.D., “Inverse Association of Dietary Calcium With Systolic Blood Pressure in Young Children”, From the Evans section of Preventive Medicine and Epidemiology, Boston School of Medicine, Dr Gillman is the recipient of a Physician Investigator Award, American Heart Association.
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“The results of our investigation show that the high calcium diet blunts the development of high blood pressure and may protect against the development of hypertension”.
Wasswa Semafuko, and David Morris, “Effect of High Calcium Diet on the Development of High Blood Pressure”, Department of Pathology and Laboratory Medicine, The Miriam Hospital Division of Biology and Medicine, Brown University, Providence Rhode Island, USA.
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“The systolic and diastolic arterial blood pressures of rats fed calcium were significantly lower compared to rats of the other groups”.
N Buassi, “High Dietary Calcium Decreases Blood Pressure in rats”, Department de Ciencias Fisiologicas, Centro de Ciencias Biologicas Universidade Estadual de Londrina, Brasil
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“The results of our research indicate that calcium restriction accelerates salt-induced hypertension”
M Nakamura, M.D., H Suzuki, M.D., H Yamakawa, M.D., Y Ohno, M.D., T Saruta, M.D., “Calcium Restriction Accelerates Salt-Induced Hypertension”, Department of Internal Medicine, Scholl of Medicine, University of Tokyo, Japan
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“Calcium intake has been implicated as being important in the development and treatment of hypertension”.
R. Schieffer, and A. Gairard, “Blood Pressure Effects of Calcium Intake in Experimental Models of Hypertension”, Institut de Recherche contre les Cancers, Hopitaux Universitaires, Strasburg, Faculte de Pharmacie, Universite Louis Pasteur, France.
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“More than 80 studies have reported lowered blood pressure after dietary calcium enrichment in experimental models of hypertensions.”
D,C, Hatton and D.A. McCarron, Dietary calcium and blood Pressure in Experimental Models of Hypertension”, Hypertension, 1994, April 23, (4):513-30, Division of Nephrology and Hypertension, Oregon Health Sciences University, Portland.
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“Low calcium in the diet is a mechanism increasing systolic blood pressure”
K.J. Lai, K Dakshinamurti, The Relationship Between Low-Calcium-Induced Increase in systolic Blood Pressure”, Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Manitoba, Canada.
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“Dietary calcium supplementation normalizes blood pressure in rats and may prevent hypertension”.
t. Butler, J. Cameron, K Kirchner, “Dietary calcium Supplementation Restores blood Pressure in Rats”, Jackson State university, Mississippi, Am J Hypertens, 1995 June 8 (6):615-21.
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“High levels of dietary calcium attenuate the elevation of arterial blood pressure induce by salt in dogs”
Emmanuel Bravo and Yo Kageyama, “Dietary Calcium Supplementation Prevents the Development of Hypertension in Salt-Treated Dogs”, Endocrine/Hypertension Research Laboratory, Research Institute Cleveland, Department of Internal Medicine, National Tochigi Hospital, Japan.
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“The blood pressure-lowering effects of dietary calcium is associated with blunting of thrombin-induced increase in platelet cytosolic calcium”.
Ramachandra Rao, Youxhen Yan, and Yanyuan Wu., “Dietary Calcium Reduces Blood Pressure” Calcium Hypertension Research Lab, Charles R Drew University of Medicine and Science, Los Angeles, California.
Scientific Publication Quotations on Calcium and Kidney Stone Health Claims
“Two powerful prospective observational studies have suggested that increased dietary calcium reduces the risk of kidney stones”.
H. Heller, “The Role of Calcium in the Prevention of Kidney Stones”, University of Texas Southwestern Medical Center at Dallas, Texas. J. Am Coll Nutr, 1999 Oct 18, (5 Suppl):373S-378S.
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“Recent evidence suggests that dietary calcium restriction may actually increase the risk of kidney stones and dietary restriction of calcium should be avoided in patients who have kidney stones”.
G. Curhan, M.D., “Dietary Calcium and Kidney Stone Formation”, Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Boston, Mass.
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“Dietary calcium intake was inversely associated with the risk of kidney stones”
Gary Curhan, M.D., Walter Willet, M.D., Eric Rimm, Sc.D., and Meir Stampfer, M.D., “A Prospective Study of Dietary Calcium and the Risk of Kidney Stones”, Department of Epidemiology and Nutrition, Harvard School of Public Health, Veterans Affairs Medical Center, Boston Mass
Scientific Publication Quotations on Calcium and Bone Fracture Health Claims
“In 12 of the 19 studies on bone loss in which calcium intake was controlled, all 12 studies showed that calcium conferred a significant benefit”.
R Henley, “Calcium and Osteoporosis: How Much is Enough”, New England Journal of Medicine, 1993;328: 503-505, Pharmaceutical Information Associates Ltd.,
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“The capacity of compensatory mechanisms to provide sufficient calcium to offset daily losses from the body declines with age, hence, increasingly the body tears down bone to access its calcium”.
Robert Heaney, M.D., FACN, “Calcium Needs of the Elderly to Reduce Fracture Risk”, Creighteon University, Osteoporosis Research Center, Omaha, Nebraska, Presented at the 41st Annual Meeting pf the American College of Nutrition at Las Vegas, Nevada, Oct 12, 2000.
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“This review supports the current and public health policy of recommending increased calcium intake among older women for fracture prevention”
Robert Cumming and Michael Nevitt, Department of Public Health and Community Medicine, University of Sydney, Australia, Journal of Bone and Mineral Research, Vol. 12, Number 9, 1997.
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“A preventive effect on the risk of hip fracture may partly be achieved by using calcium supplements for a late prevention in elderly people”
P Meunier, “Prevention of Hip Fractures by Correcting Calcium Insufficiencies in Elderly People”, Dept of Rheumat and Bone Disease Hospital Edouard Herriot, Lyon, France
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“In elderly women low calcium absorption and intake increases the risk of hip fracture”.
Kristine Ensrud, M.D., Tu Duong, Jane Cauley, Robert Heaney, M.D., Randi Wolf, PhD., Emily Harris, PhD., Steven Cummings, M.D., “Low Fractional Calcium Absorption Increase the Risk for Hip Fracture in Women With Low Calcium Intake”, Study of Osteoporotic Fractures Research Group, Ann Intern Med, 2000;132:345-353.
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“Thus, oral calcium supplements prevented a femoral bone mineral density decrease and lowered vertebral fracture rate in the elderly”.
T Chevalley, R Rizzoli, V. Nydegger, D Slosman, C Rapin, Jmichel, H Vasey, and J Bonjour, Effects of Calcium Supplements on Femoral Bone Mineral Density and Vertebral Fracture Rate in Patients”, World Health Organization for Osteoporosis and Bone Disease, Department of Medicine, University Hospital of Geneva, Switzerland.
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“Intake of 1000mg of calcium seems necessary to maintain bone health in postmenopausal women and if this level cannot be achieved by diet, calcium supplements should be given”.
Anthony Albanese, PhD., Calcium Nutrition in the Elderly”, Burke Rehabilitation Center, White Plains, New York.
Scientific Publication Quotations on Calcium and Menstrual Disorders Health Claims
“Based on available evidence, a strong statement can be made regarding the importance of ensuring calcium intake in all women, particularly those in post-menopause”.
The North American Menopause Society (NAMS), “The Role of Calcium in Postmenopausal Women: consensus opinion of the North American Menopause Society”, Menopause 2001, March 8 (2):84-95.
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“Calcium supplementation is a simple and effective treatment for premenstrual syndrome”.
Susan Thys-Jacobs, M.D., Silvo Ceccarelli, M.D., Arlene Bierman, M.D., Henry Weisman, M.D., Mary Cohen, M.D., Jose Alivir, DrPH, “Calcium Supplementation in Premenstrual Syndrome”, Department of Medicine Metropolitan Hospital, New York Medical College, New York, Society of General Internal Medicine in Washington, D.C.,
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“Within two months of calcium therapy, two pre-menopausal women with a history of menstrual-related migraines and premenstrual syndrome both cited a major reduction in their headache attacks as well as premenstrual symptoms”.
Susan Thys-Jacobs M.D., “Vitamin D and Calcium in Menstrual Migraine”, Division of General Internal medicine, Mount Sinai Hospital, April 11, 1994.
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“Calcium supplementation, 1200 to 1600mg daily, should be considered a sound treatment option in women who experience premenstrual syndrome”.
Michael Ward and Teresa Holimon, “Calcium Treatment for Premenstrual Syndrome”,
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“Calcium supplementation reduced the negative effect , water retention, and pain, during the menstrual phase”.
Jose Alvir, DrP.H., and Susan Thys-Jacobs, M.D., “Premenstrual Symptom and Response to Calcium Treatment”, Hillside Hospital, Division of Long Island Jewish Medical Center, Glen Oaks, New York, Vol. 27, No. 2, 1991.
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“Clinical trials in women with PMS have found that calcium supplementation effectively alleviates the majority of mood an somatic symptoms.”
Susan Thys-Jacobs, M.D., “Micronutrients and the Premenstrual Syndrome: The Case for Calcium”, Clinical Director, Metabolic Bone Center, St. Luke’s Roosevelt Hospital, Columbia University, New York
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